Precision determination of the CKM element V_cb

We extract the magnitude of the CKM matrix element Vcb and the most relevant parameters of the Heavy Quark Expansion from data of inclusive semileptonic B decays. Our calculation includes the recently computed O(alphas Lambda^2/mb^2) corrections and a careful estimate of the residual theoretical uncertainty. Using a recent determination of the charm quark mass, we obtain |Vcb| = (42.21+-0.78)x10-3 and mb_kin(1GeV)=(4.553+-0.020)GeV.