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Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of In Vitro Wound-Healing and Anti-Inflammatory Activities

Articolo
Data di Pubblicazione:
2020
Abstract:
The winemaking process produces a huge number of pomaces that generally are used for energy purposes. Further valuable applications such as health-promoting properties are still under investigation. The seeds of the white berries of Mantonico and Pecorello cv. were extracted in a Soxhlet apparatus, using n-hexane and chloroform as solvents. Extracts were characterized by NMR and GC-MS analyses. They were assayed in vitro as wound healing and anti-inflammatory agents in HaCaT and RAW 264.7 cell lines, respectively. n-hexane Mantonico extract resulted in the most interesting wound healing sample, while n-hexane Pecorello, containing a good number of carotenoids, resulted in a good anti-inflammatory candidate. These preliminary findings underlined the benefit of grape seed extracts valorization due to their health-promoting properties.
Tipologia CRIS:
03A-Articolo su Rivista
Keywords:
Soxhlet; grape seeds; anti-inflammatory; wound healing; lipophilic fraction; carotenoids; HaCaT cell line; RAW 264.7 cell line; NMR; GC-MS
Elenco autori:
Carullo G., Sciubba F., Governa P., Mazzotta S., Frattaruolo L. ,Grillo G., Cappello A.R., Cravotto G., Di Cocco M.E., Aiello F.
Autori di Ateneo:
CRAVOTTO Giancarlo
Link alla scheda completa:
https://iris.unito.it/handle/2318/1741444
Link al Full Text:
https://iris.unito.it/retrieve/handle/2318/1741444/616377/pharmaceuticals-13-00097-v2.pdf
https://iris.unito.it/retrieve/handle/2318/1741444/616379/pharmaceuticals-13-00097-s001.pdf
Pubblicato in:
PHARMACEUTICALS
Journal
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URL

https://www.mdpi.com/1424-8247/13/5/97
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