Silica gel-immobilised chiral 1,2- benzenedisulfonimide: a Brønsted acid heterogeneous catalyst for enantioselective multicomponent Passerini reaction

A chiral heterogeneous catalyst derivative of ()-4,5-dimethyl-3,6-bis(1-naphthyl)-1,2- benzenedisulfonimide is proven here to be efficient in a three-component asymmetric Passerini protocol, carried out in a deep eutectic solvent. Reaction conditions are mild and green, while enantioselectivity is excellent. The catalyst was easily recovered and reused with no decrease in its catalytic activity.