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  1. Pubblicazioni

West Asian sources of the Eurasian component in Ethiopians: a reassessment

Articolo
Data di Pubblicazione:
2019
Abstract:
The presence of genomic signatures of Eurasian origin in contemporary Ethiopians has been reported by several authors and estimated to have arrived in the area from 3000 years ago. Several studies reported plausible source populations for such a signature, using haplotype based methods on modern data or single-site methods on modern or ancient data. These studies did not reach a consensus and suggested an Anatolian or Sardinia-like proxy, broadly Levantine or Neolithic Levantine as possible sources. We demonstrate, however, that the deeply divergent, autochthonous African component which accounts for ~50% of most contemporary Ethiopian genomes, affects the overall allele frequency spectrum to an extent that makes it hard to control for it and, at once, to discern between subtly different, yet important, Eurasian sources (such as Anatolian or Levant Neolithic ones). Here we re-assess pattern of allele sharing between the Eurasian component of Ethiopians (here called “NAF” for Non African) and ancient and modern proxies. Our results unveil a genomic legacy that may connect the Eurasian genetic component of contemporary Ethiopians with Sea People and with population movements that affected the Mediterranean area and the Levant after the fall of the Minoan civilization.
Tipologia CRIS:
03A-Articolo su Rivista
Keywords:
African Continental Ancestry Group; Asian Continental Ancestry Group; Ethiopia; Gene Frequency; Genetics, Population; Genomics; Humans; Phylogeny; Genetic Variation; Genome, Human; Human Migration
Elenco autori:
Molinaro L.; Montinaro F.; Yelmen B.; Marnetto D.; Behar D.M.; Kivisild T.; Pagani L.
Autori di Ateneo:
MARNETTO Davide
Link alla scheda completa:
https://iris.unito.it/handle/2318/1845607
Link al Full Text:
https://iris.unito.it/retrieve/handle/2318/1845607/951605/s41598-019-55344-y.pdf
Pubblicato in:
SCIENTIFIC REPORTS
Journal
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