Data di Pubblicazione:
2021
Abstract:
Introduction: Patients on dialysis (HDPs) are a category at high risk from COVID-19 and thus a high-priority
group for vaccination. COVID-19 vaccine hesitancy has been a concern since the availability of the first
vaccine. The objective of this study was to determine hesitancy rates and factors associated with hesitancy
toward COVID-19 vaccination in HDP.
Methods: HDP were surveyed with an ad hoc questionnaire in 4 large dialysis facilities in Europe: Le Mans
and Paris, in France, and Cagliari and Pavia, in Italy. The questionnaire explored different domains
associated with vaccine hesitancy, such as perception of disease severity, sources of information about
the vaccine and the disease, and confidence in the health care system.
Results: A total of 417 patients (average age 69 years, 60% men) agreed to answer the questionnaire.
Hesitancy was associated with younger age (P ¼ 0.003), lower perception of disease severity (P < 0.001)
and vaccine efficacy (P < 0.001), and lower trust in vaccination (P < 0.001) and in the health care system
and scientists (P < 0.001) in the univariate analysis. In the multivariate models, concerns about side effects
(P ¼ 0.004) and vaccine efficacy (P < 0.001) and living in France (P ¼ 0.04) remained associated with higher
vaccine hesitancy, whereas having received an influenza vaccine (P ¼ 0.032) and trusting scientists (P ¼
0.032) were associated with a more positive attitude toward vaccination.
Conclusions: HDPs have a good understanding of the risks associated with COVID-19. Vaccine hesitancy
was not associated with educational level, age, or gender but rather with lack of confidence in vaccine
efficacy and concerns about safety. HDPs were quite skeptical about the health care system but generally
trusted scientists.
Tipologia CRIS:
03A-Articolo su Rivista
Keywords:
COVID-19; dialysis; hesitancy; SARS-CoV-2; vaccine
Elenco autori:
Bianchi S, Torreggiani M, Chatrenet A ,Fois A , Mazé B , Njandjo L, Bianco G, Lepori L, Pili A ,Michel PA, Sileno G, Arazzi M, Esposito V, Pani A , Versino E, Esposito C, Fessi H, Cabiddu G, Piccoli GB
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