Data di Pubblicazione:
2003
Abstract:
Experiments of in vitro formation of blood vessels show that cells randomly spread on a gel matrix autonomously organize to form a connected vascular network. We propose a simple model which reproduces many features of the biological system. We show that both the model and the real system exhibit a fractal behavior at small scales, due to the process of migration and dynamical aggregation, followed at large scale by a random percolation behavior due to the coalescence of aggregates. The results are in good agreement with the analysis performed on the experimental data.
Tipologia CRIS:
03A-Articolo su Rivista
Keywords:
Morphogenesis; Burgers dynamics; blood vessels; migration and dynamical aggregation
Elenco autori:
GAMBA A; AMBROSI D; CONIGLIO A; DE CANDIA A; DI TALIA S; E. GIRAUDO; SERINI G; PREZIOSI L; BUSSOLINO F
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