Novel azobenzene derivatives containing a glucopyranoside moiety. Part I: synthesis, characterisation and mutagenic properties

The synthesis of dimethylaminoazobenzene derivatives containing a beta-D-glucopyranosyl ring is described. Structures have been defined by H-1 NMR techniques, selective decoupling and H-1-H-1 COSY. Differential thermal analysis. (DTA) and thermogravimetry (TG) have been used to describe their thermal behaviour. Genotoxicity (Ames test) comparisons with their p-methoxy counterparts have shown the effect of beta-D-glucopyranosyl on reducing the mutagenicity.