Early B Cell and Plasma Cell Kinetics Upon Treatment Initiation Portend Flares in Systemic Lupus Erythematosus: A Post-Hoc Analysis of Three Phase III Clinical Trials of Belimumab

Articolo
Data di Pubblicazione:
2022
Abstract:
To investigate changes in B cell subsets in relation to disease flares upon initiation of standard therapy (ST) plus belimumab or placebo in patients with systemic lupus erythematosus (SLE).
Tipologia CRIS:
03A-Articolo su Rivista
Keywords:
B cells; belimumab; biologics; biomarkers; flares; plasma cells; systemic lupus erythematosus; Antibodies; Monoclonal; Humanized; Complement System Proteins; Humans; Kinetics; Severity of Illness Index; Treatment Outcome; Lupus Erythematosus; Systemic; Plasma Cells
Elenco autori:
Parodis I.; Gomez A.; Chow J. W.; Borg A.; Lindblom J.; Gatto M.
Autori di Ateneo:
GATTO Mariele
Link alla scheda completa:
https://iris.unito.it/handle/2318/1939351
Link al Full Text:
Pubblicato in:
FRONTIERS IN IMMUNOLOGY
Journal