Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma
Articolo
Data di Pubblicazione:
2016
Tipologia CRIS:
03A-Articolo su Rivista
Keywords:
Adenocarcinoma; Adenocarcinoma of Lung; Aged; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dasatinib; Discoidin Domain Receptor 1; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Membrane Proteins; Mice; Middle Aged; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Paclitaxel; Proto-Oncogene Proteins p21(ras); Receptor Protein-Tyrosine Kinases; Receptors, Notch; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction
Elenco autori:
Ambrogio C.; Gomez-Lopez G.; Falcone M.; Vidal A.; Nadal E.; Crosetto N.; Blasco R.B.; Fernandez-Marcos P.J.; Sanchez-Cespedes M.; Ren X.; Wang Z.; Ding K.; Hidalgo M.; Serrano M.; Villanueva A.; Santamaraa D.; Barbacid M.
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