Within-breath oscillatory mechanics in horses affected by severe equine asthma in exacerbation and in remission of the disease
Articolo
Data di Pubblicazione:
2022
Abstract:
Oscillometry is a technique that measures the resistance (R) and the reactance (X) of the respiratory system. In humans, analysis of inspiratory and expiratory R and X allows to identify the presence of tidal expiratory flow limitation (EFLt). The aim of this study was to describe inspiratory and expiratory R and X measured by impulse oscillometry system (IOS) in horses with severe asthma (SEA) when in clinical remission (n = 7) or in exacerbation (n = 7) of the condition. Seven healthy, age-matched control horses were also studied. Data at 3, 5, and 7 Hz with coherence > 0.85 at 3 Hz and >0.9 at 5 and 7 Hz were considered. The mean, inspiratory and expiratory R and X and the difference between inspiratory and expiratory X (∆X) were calculated at each frequency. The data from the three groups were statistically compared. Results indicated that in horses during exacerbation of severe asthma, X during expiratory phase is more negative than during inspiration, such as in humans in presence of EFLt. The evaluation of X during inspiration is promising in discriminating between horses with SEA in remission and control horses.
Tipologia CRIS:
03A-Articolo su Rivista
Keywords:
Airway obstruction; Equine asthma; Impulse oscillometry; Lung function test
Elenco autori:
Stucchi L.; Ferrucci F.; Bullone M.; Dellaca R.L.; Lavoie J.P.
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