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Beyond the Prognostic Value of 2-[18F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management

Articolo
Data di Pubblicazione:
2022
Abstract:
The role of 2-deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) in the management of prostate cancer (PCa) patients is increasingly recognised. However, its clinical role is still controversial. Many published studies showed that FDG PET/CT might have a prognostic value in the metastatic castration-resistant phase of the disease, but its role in other settings of PCa and, more importantly, its impact on final clinical management remains to be further investigated. We describe a series of six representative clinical cases of PCa in different clinical settings, but all characterised by a measurable clinical impact of FDG PET/CT on the patients' management. Starting from their clinical history, we report a concise narrative literature review on the advantages and limitations of FDG PET/CT beyond its prognostic value in PCa. What emerges is that in selected cases, this imaging technique may represent a useful tool in managing PCa patients. However, in the absence of dedicated studies to define the optimal clinical setting of its application, no standard recommendations on its use in PCa patients can be made.
Tipologia CRIS:
03A-Articolo su Rivista
Keywords:
18F-Fluorodeoxyglucose; diagnosis; positron emission tomography; prostate cancer; staging; treatment response assessment
Elenco autori:
Borea, Roberto; Favero, Diletta; Miceli, Alberto; Donegani, Maria Isabella; Raffa, Stefano; Gandini, Annalice; Cremante, Malvina; Marini, Cecilia; Sambuceti, Gianmario; Zanardi, Elisa; Morbelli, Silvia; Fornarini, Giuseppe; Rebuzzi, Sara Elena; Bauckneht, Matteo
Autori di Ateneo:
MORBELLI Silvia Daniela
Link alla scheda completa:
https://iris.unito.it/handle/2318/1956412
Link al Full Text:
https://iris.unito.it/retrieve/handle/2318/1956412/1239713/diagnostics-12-00581.pdf
Pubblicato in:
DIAGNOSTICS
Journal
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